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4G光元：韩国大学的一个研究小组开发了一种可以用甲烷生产甲醇的生物材料，甲醇被认为是替代汽油柴油，未来世界绿色环保有潜力的液体液体燃料，甲烷是地球上最丰富的天然气资源之一。 由韩国大学Lee Ji-won教授领导的一个研究小组于4月2日宣布，它已经成功地使用甲烷氧化细菌的生物过程开发酶促纳米粒子。 甲烷气体是天然气，页岩气，垃圾填埋场沼气和生物气体的主要成分，是用于生产甲醇的最佳原材料。甲烷可以转化为甲醇，作为替代原油可以用于生产各种家庭用品和主要工业材料。 然而，在传统的甲烷生产甲醇的过程中，甲烷气体的化学氧化过程在技术，经济和环境方面存在许多问题，包括高能耗，环境污染和低反应转化率。作为生产甲醇化学过程的替代方案，研究团队通过生物过程创造了酶纳米粒子，该生物过程仅使用甲烷单氧化酶（MMO）的关键活性位点。 MMO以膜蛋白的形式存在，是一种具有高工业价值的酶，因为它可以在非常温和的条件（45摄氏度）下选择性地将甲烷转化为甲醇。然而，培养高浓度的甲烷氧化细菌非常困难，并且也难以大规模生产MMO。 研究小组制造的纳米颗粒使用大肠杆菌（E. coli），可以在短时间内高浓度生长，大规模生产MMO。可以长时间重复使用。 Lee说：“我们开发出可以大规模生产甲烷单氧化酶的纳米粒子和能够稳定地重复使用酶纳米粒子的生产系统，这是有意义的。它将有助于开发具有工业价值和高价值的各种酶。效率生物过程。“ 该研究的结果发表在国际期刊Nature Catalysis（4月2日）上。 纳米粒子用于大规模生产甲烷单氧化酶 Nanoparticles Used to Mass-produce Methane Monooxidase Korean Research Team Develops Methanol-Producing Biomaterial with High Efficiency A Korea University research team has developed a biomaterial that can produce methanol from methane. A Korean research team has developed a biomaterial that can produce methanol from methane, which is one of the most abundant gas resources on the planet. A research team led by Professor Lee Ji-won at Korea University announced on April 2 that it has succeeded in developing enzymatic nanoparticles using a bio-process that uses methane-oxidizing bacteria. Methane gas is a main component of shale, landfill, and biogases and is a raw material used to produce methanol. Methane can be converted into methanol, which can be used in the production of various household goods and major industrial materials by replacing crude oil. However, the chemical oxidation process of producing methane gas has many problems in terms of technical, economic and environmental aspects, including high energy consumption, environmental pollution, and a low reactive conversion rate. As an alternative to the chemical process of producing methanol, the research team created enzyme nanoparticles through a bioprocess that only uses the key active sites of methane monooxidase (MMO). MMO, which is present in the form of membrane protein, is an enzyme with a high industrial value because it can selectively convert methane to methanol at a very mild condition (45 degrees Celsius). However, it is very difficult to cultivate high concentration of methanotrophic bacteria, and it is also difficult to mass-produce MMO. The nanoparticles made by the research team use E. coli, which is easily grown at high concentrations in a short time, to mass produce MMO. In addition, when the enzyme nanoparticles are immobilized on the porous hydrogel, their activity is stably maintained and can be reused repeatedly for a long time. Lee said, "It is meaningful that we have developed nanoparticles that can mass-produce methane monooxidase and a production system capable of reusing enzyme nanoparticles stably and repeatedly. It will be able to contribute to the development of various enzymes with industrial value and high-efficiency bio-processes." The results of the study are published in international journal Nature Catalysis (April 2). 声明：本站部分 章内容系出于传递信息之目的源自于第三方 站转载，行业企业、终端用户投稿。若对稿件内容有任何疑问或质疑，请立即与本 站联系，本 站将迅速给予回应并第一时间做出处理（联系邮箱：jinwei@zod.com.cn）。
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